Bumrah reaches career-best third position in bowlers list led by Hasan Ali.
David Miller smashed the fastest century in T20I as South Africa outclassed Bangladesh by 83 runs at Senwes Park on Sunday.
The hosts will look to maintain its unbeaten streak and end the series with another sweep.
Bangladesh remains winless on tour as it falls short of 196-run target in first T20I.
South Africa will miss du Plessis in the T20I series, but might still have enough firepower to continue its dominant run.
Faf du Plessis sustained an acute left lumbar (lower-back) strain. JP Duminy will be leading the Proteas in his absence.